The Binding of Androsterone Sulfate, Etiocholanolone Sulfate, and Dehydroisoandrosterone Sulfate by Human Plasma Protein*
نویسندگان
چکیده
منابع مشابه
Isolation of Androsterone Sulfate
It has long been recognized that many of the steroids, including the androgens, are excreted in urine in conjugation with other substances which render them not only more water-soluble but also neutralize their physiological activity to a great extent. In 1936 Cohen and Marrian (1) isolated estriol glucuronide, the conjugated form of estriol, from the urine of pregnant women and in 1936 Venning...
متن کاملMetabolism of dehydroepiandrosterone sulfate and estrone-sulfate by human platelets.
The aim of the present research was to study the uptake of DHEAS, and to establish the intracrine capacity of human platelets to produce sex steroid hormones. The DHEAS transport was evaluated through the uptake of [(3)H]-DHEAS in the presence or absence of different substrates through the organic anion transporting polypeptide (OATP) family. The activity of sulfatase enzyme was evaluated, and ...
متن کاملAbnormal 24-hr mean plasma concentrations of dehydroisoandrosterone and dehydroisoandrosterone sulfate in women with primary operable breast cancer.
The 24-hr mean plasma concentrations of dehydroisoandrosterone (DHA) and dehydroisoandrosterone sulfate were measured in 11 women with primary operable breast cancer, ages 31 to 78 years, and in 37 normal women, ages 21 to 75 years. In contrast to the marked and progressive decline of DHA and dehydroisoandrosterone sulfate concentration with age in the normal women, the concentrations of both s...
متن کامل[Studies on solvolysis of dehydroepiandrosterone and androsterone sulfate].
Although heated strong acid hydrolysis has been generally adopted as the routine procedure for the hydrolysis of urinary steroids, it has disadvantages such as the destruction of the steroids, the production of artifacts, and the remarkable changes of the pattern of the fractionation. As for the glucuronide types of the urinary steroids, the .-glucuronidase method can now be used instead of thi...
متن کاملThe binding of cations by chondroitin sulfate.
The polyelectrolyte nature of chondroitin sulfate and related polysaccharides suggests they may bind cations. Since chondroitin sulfate is an extracellular component of mammalian connective tissue, the binding properties of this polyelectrolyte for cations may be of significance in the distribution and storage of extracellular cations. In disease states in which sodium is known to play a major ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1965
ISSN: 0021-9738
DOI: 10.1172/jci105229